{"created":"2023-06-19T11:24:45.466909+00:00","id":5519,"links":{},"metadata":{"_buckets":{"deposit":"a6f783c2-c4d6-4fab-9811-11f4261aa1bf"},"_deposit":{"created_by":1,"id":"5519","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"5519"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00005519","sets":["7","7:24"]},"author_link":["17291","17294","17292","17293","17295","17297","17296"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-02-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"224","bibliographicPageStart":"221","bibliographicVolumeNumber":"69","bibliographic_titles":[{"bibliographic_title":"Journal of Veterinary Medical Science"}]}]},"item_5_description_28":{"attribute_name":"識別番号 その他","attribute_value_mlt":[{"subitem_description":"PMID:17339771","subitem_description_type":"Other"}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Mannan-binding lectin (MBL) and bovine conglutinin (BKg) belong to the collectin family, which is involved in first-line host defense against various infectious agents. We have previously reported that human MBL inhibited type A influenza viral hemagglutination, infection and spreading to adjacent cells without complement activation. In this study, we investigated the direct antiviral activities of bovine MBL, rabbit MBL and BKg. All collectins used in this study inhibited viral infectivity and hemagglutination at concentrations of 0.02-0.3 μg/ml. They also demonstrated inhibitory activity against viral spreading. Like human MBL, bovine MBL and BKg showed antiviral activities at their physiological concentrations. These results suggest that mammalian MBLs and BKg may inhibit the spread of influenza A virus through the bloodstream.","subitem_description_type":"Abstract"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_relation_24":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1292/jvms.69.221","subitem_relation_type_select":"DOI"}}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0916-7250","subitem_source_identifier_type":"ISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"17339771"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"708"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"552"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Kawai, Takao"},{"subitem_text_value":"Kase, Tetsuo"},{"subitem_text_value":"Suzuki, Yasuhiko"},{"subitem_text_value":"Eda, Souji"},{"subitem_text_value":"Sakamoto, Takashi"},{"subitem_text_value":"Ohtani, Katsuki"},{"subitem_text_value":"Wakamiya, Nobutaka"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"河合, 高生"},{"creatorName":"カワイ, タカオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17291","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加瀬, 哲男"},{"creatorName":"カセ, テツオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17292","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木, 定彦"},{"creatorName":"スズキ, ヤスヒコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17293","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"江田, 宗司"},{"creatorName":"エダ, ソウジ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17294","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"坂本, 隆志"},{"creatorName":"サカモト, タカシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17295","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大谷, 克城"},{"creatorName":"オオタニ, カツキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17296","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"若宮, 伸隆"},{"creatorName":"ワカミヤ, ノブタカ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17297","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"6532.pdf","filesize":[{"value":"2.8 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"6532.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/5519/files/6532.pdf"},"version_id":"a69c0d63-afd1-424b-a85b-39faf3b007db"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"conglutinin","subitem_subject_scheme":"Other"},{"subitem_subject":"influenza A virus","subitem_subject_scheme":"Other"},{"subitem_subject":"mannan-binding lectin","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Anti-Influenza A Virus Activities of Mannan-Binding Lectins and Bovine Conglutinin","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Anti-Influenza A Virus Activities of Mannan-Binding Lectins and Bovine Conglutinin"}]},"item_type_id":"5","owner":"1","path":["6","7","24"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-08-22"},"publish_date":"2016-08-22","publish_status":"0","recid":"5519","relation_version_is_last":true,"title":["Anti-Influenza A Virus Activities of Mannan-Binding Lectins and Bovine Conglutinin"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-19T12:19:21.387371+00:00"}