{"created":"2023-06-19T11:24:45.399651+00:00","id":5518,"links":{},"metadata":{"_buckets":{"deposit":"f366c8bd-7272-44d9-8358-570901bdd204"},"_deposit":{"created_by":1,"id":"5518","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"5518"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00005518","sets":["7","7:24"]},"author_link":["17280","17277","17278","17286","17287","17290","17288","17284","17281","17285","17282","17279","17289","17283"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015-07-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"11","bibliographicPageStart":"1","bibliographicVolumeNumber":"10","bibliographic_titles":[{"bibliographic_title":"PLoS One"}]}]},"item_5_description_28":{"attribute_name":"識別番号 その他","attribute_value_mlt":[{"subitem_description":"PMID:26173080","subitem_description_type":"Other"}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Understanding the molecular components of immune recognition of the tuberculosis (TB) bacillus, Mycobacterium tuberculosis, can help designing novel strategies to combat TB. Here, we identify collectin CL-LK as a novel soluble C-type lectin able to bind M. tuberculosis, and characterize mycobacterial mannose-capped lipoarabinomannan as a primary ligand for CL-LK. Mice deficient in CL-K1, one of the CL-LK subunits, do not display altered susceptibility to M. tuberculosis. However, we found that the amount of CL-LK in the serum of patients with active TB is reduced, compared to that in controls, and correlates inversely to the magnitude of the immune response to the pathogen. These findings indicate that CL-LK might be of interest for future diagnostic and treatment monitoring purposes.","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Open Access","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_relation_24":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1371/journal.pone.0132692","subitem_relation_type_select":"DOI"}}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1932-6203","subitem_source_identifier_type":"ISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"26173080"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"591"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"611"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"&EMPTY&"},{"subitem_text_value":"&EMPTY&"},{"subitem_text_value":"&EMPTY&"},{"subitem_text_value":"&EMPTY&"},{"subitem_text_value":"&EMPTY&"},{"subitem_text_value":"Mori, Ken-ichiro"},{"subitem_text_value":"Ohtani, Katsuki"},{"subitem_text_value":"&EMPTY&"},{"subitem_text_value":"&EMPTY&"},{"subitem_text_value":"&EMPTY&"},{"subitem_text_value":"&EMPTY&"},{"subitem_text_value":"&EMPTY&"},{"subitem_text_value":"Wakamiya, Nobutaka"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Anthony, Troegeler"}],"nameIdentifiers":[{"nameIdentifier":"17277","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Geanncarlo, Lugo-Villarino"}],"nameIdentifiers":[{"nameIdentifier":"17278","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Søren, Hansen"}],"nameIdentifiers":[{"nameIdentifier":"17279","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Voahangy, Rasolofo"}],"nameIdentifiers":[{"nameIdentifier":"17280","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Maiken, Lumby  Henriksen"}],"nameIdentifiers":[{"nameIdentifier":"17281","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森, 健一郎"},{"creatorName":"モリ, ケンイチロウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17282","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大谷, 克城"},{"creatorName":"オオタニ, カツキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17283","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Carine, Duval"}],"nameIdentifiers":[{"nameIdentifier":"17284","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ingrid, Mercier"}],"nameIdentifiers":[{"nameIdentifier":"17285","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Alan, Benard"}],"nameIdentifiers":[{"nameIdentifier":"17286","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Jerome, Nigou"}],"nameIdentifiers":[{"nameIdentifier":"17287","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Denis, Hudrisier"}],"nameIdentifiers":[{"nameIdentifier":"17288","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"若宮, 伸隆"},{"creatorName":"ワカミヤ, ノブタカ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17289","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Olivier, Neyrolles"}],"nameIdentifiers":[{"nameIdentifier":"17290","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"6529.pdf","filesize":[{"value":"690.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"6529.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/5518/files/6529.pdf"},"version_id":"2ff25d14-9447-423a-ae31-68091802758e"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Collectin CL-LK is a Novel Soluble Pattern Recognition Receptor for Mycobacterium tuberculosis","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Collectin CL-LK is a Novel Soluble Pattern Recognition Receptor for Mycobacterium tuberculosis"}]},"item_type_id":"5","owner":"1","path":["6","7","24"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-08-17"},"publish_date":"2016-08-17","publish_status":"0","recid":"5518","relation_version_is_last":true,"title":["Collectin CL-LK is a Novel Soluble Pattern Recognition Receptor for Mycobacterium tuberculosis"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-19T12:19:23.633962+00:00"}