{"created":"2023-06-19T11:24:36.885187+00:00","id":5355,"links":{},"metadata":{"_buckets":{"deposit":"e31cdda6-ab12-4239-b38b-7adac3839c46"},"_deposit":{"created_by":1,"id":"5355","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"5355"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00005355","sets":["7","7:24"]},"author_link":["16780","16779","16781","16782","16783"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-12-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"12","bibliographicPageEnd":"1278","bibliographicPageStart":"1272","bibliographicVolumeNumber":"59","bibliographic_titles":[{"bibliographic_title":"Archives of Oral Biology"}]}]},"item_5_description_28":{"attribute_name":"識別番号 その他","attribute_value_mlt":[{"subitem_description":"PMID:25150532","subitem_description_type":"Other"}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"OBJECTIVES:\n\\nA large number of neurons are generated at the subventricular zone (SVZ) even during adulthood. In a previous study, we have shown that a reduced mastication impairs both neurogenesis in the SVZ and olfactory functions. Pheromonal signals, which are received by the vomeronasal organ, provide information about reproductive and social states. Vomeronasal sensory neurons project to the accessory olfactory bulb (AOB) located on the dorso-caudal surface of the main olfactory bulb. Newly generated neurons at the SVZ migrate to the AOB and differentiate into granule cells and periglomerular cells. This study aimed to explore the effects of changes in mastication on newly generated neurons and pheromonal responses.\nDESIGN:\n\\nBromodeoxyuridine-immunoreactive (BrdU-ir; a marker of DNA synthesis) and Fos-ir (a marker of neurons excited) structures in sagittal sections of the AOB after exposure to urinary odours were compared between the mice fed soft and hard diets.\nRESULTS:\n\\nThe density of BrdU-ir cells in the AOB in the soft-diet-fed mice after 1 month was essentially similar to that of the hard-diet-fed mice, while that was lower in the soft-diet-fed mice for 3 or 6 months than in the hard-diet-fed mice. The density of Fos-ir cells in the soft-diet-fed mice after 2 months was essentially similar to that in the hard-diet-fed mice, while that was lower in the soft-diet-fed mice for 4 months than in the hard-diet-fed mice.\nCONCLUSIONS:\n\\nThe present results suggest that impaired mastication reduces newly generated neurons at the AOB, which in turn impairs olfactory function at the AOB.","subitem_description_type":"Abstract"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_relation_24":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.archoralbio.2014.07.018","subitem_relation_type_select":"DOI"}}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"25150532"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"631"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"782"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Utsugi, Chizuru"},{"subitem_text_value":"Miyazono, sadaharu"},{"subitem_text_value":"Osada, Kazumi"},{"subitem_text_value":"Matsuda, Mitsuyoshi"},{"subitem_text_value":"Kashiwayanagi, Makoto"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"宇津木, 千鶴"},{"creatorName":"ウツギ, チヅル","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"16779","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"宮園, 貞治"},{"creatorName":"ミヤゾノ, サダハル","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"16780","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長田, 和実"},{"creatorName":"オサダ, カズミ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"16781","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"松田, 光悦"},{"creatorName":"マツダ, ミツヨシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"16782","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柏柳, 誠"},{"creatorName":"カシワヤナギ, マコト","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"16783","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"6161.pdf","filesize":[{"value":"414.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"6161.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/5355/files/6161.pdf"},"version_id":"6aef0645-72ea-4399-9134-87383e13cb70"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Hard diet","subitem_subject_scheme":"Other"},{"subitem_subject":"Mastication","subitem_subject_scheme":"Other"},{"subitem_subject":"Olfactory function","subitem_subject_scheme":"Other"},{"subitem_subject":"Pheromone","subitem_subject_scheme":"Other"},{"subitem_subject":"Soft diet","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Impaired mastication reduced newly generated neurons at the accessory olfactory bulb and pheromonal responses in mice.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Impaired mastication reduced newly generated neurons at the accessory olfactory bulb and pheromonal responses in mice."}]},"item_type_id":"5","owner":"1","path":["6","7","24"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-07-08"},"publish_date":"2015-07-08","publish_status":"0","recid":"5355","relation_version_is_last":true,"title":["Impaired mastication reduced newly generated neurons at the accessory olfactory bulb and pheromonal responses in mice."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-19T12:23:24.360709+00:00"}