{"created":"2023-06-19T11:24:15.278387+00:00","id":4942,"links":{},"metadata":{"_buckets":{"deposit":"12f1ed8b-3f39-43a3-aea6-562874fa3d96"},"_deposit":{"created_by":1,"id":"4942","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"4942"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00004942","sets":["7","7:23"]},"author_link":["15325"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2001-02-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"218","bibliographicPageStart":"212","bibliographicVolumeNumber":"55","bibliographic_titles":[{"bibliographic_title":"医療"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"肺高血圧症のうち一次性肺高血圧症(原発性肺高血圧症)は原因不明の疾患群を総称しているが,二次性肺高血圧症の多くは,外的刺激によって内皮細胞が障害をうけ,種々の応答を繰り返して肺血管リモデリングが進展するため,肺高血圧が発症し持続する.その結果,肺血管インピーダンスの増加をきたし,右心負荷から右心肥大・右心不全という一連の病態を引き起こす.プロスタサイクリンは肺動脈圧を下げ,心拍出量をあげ,体酸素供給を増やし,肺血管リモデリングを改善する.NOは,特異的に肺血管床のみに作用して,肺動脈圧を下げる急性効果はあるが,慢性効果については投与法も含め検討されている","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"雑誌掲載版","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_relation_27":{"attribute_name":"医中誌ID","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"2002019605","subitem_relation_type_select":"ICHUSHI"}}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0021-1699","subitem_source_identifier_type":"ISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"2002019605"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"659"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"1006"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Tobise, Katsuyuki"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"飛世, 克之"},{"creatorName":"トビセ, カツユキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"15325","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"5804.pdf","filesize":[{"value":"3.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"5804.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/4942/files/5804.pdf"},"version_id":"01a9786f-ab43-4dca-bfb2-61daa1e82a15"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"内皮障害、肺血管 remodeling、肺血管インピーダンス、プロスタサイクリン、NO","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"肺高血圧症　最近の進歩","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"肺高血圧症　最近の進歩"}]},"item_type_id":"5","owner":"1","path":["6","7","23"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-07-08"},"publish_date":"2014-07-08","publish_status":"0","recid":"4942","relation_version_is_last":true,"title":["肺高血圧症　最近の進歩"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-19T12:33:02.867927+00:00"}