{"created":"2023-06-19T11:24:05.965828+00:00","id":4754,"links":{},"metadata":{"_buckets":{"deposit":"efb39aef-f722-43a8-b61b-d52cfa20d71d"},"_deposit":{"created_by":3,"id":"4754","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"4754"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00004754","sets":["7","7:23"]},"author_link":["14741","14742"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-04-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"139","bibliographicPageEnd":"133","bibliographicPageStart":"122","bibliographic_titles":[{"bibliographic_title":"ENTONI"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"抗好中球細胞質抗体(ANCA)関連血管炎は、顕微鏡的多発血管炎、多発血管炎性肉芽腫症(ウェゲナー肉芽腫症)、好酸球性肉芽腫性多発血管炎(アレルギー性肉芽腫性血管炎、Churg-Strauss症候群)からなる。ANCAには、PR3-ANCA(C-ANCA)とMPO-ANCA(P-ANCA)があり、PR3-ANCAは多発血管炎性肉芽腫症、MPO-ANCAは顕微鏡的多発血管炎、好酸球性肉芽腫性多発血管炎の疾患マーカーである。本疾患群は、初診時にはANCAや組織所見の陽性率が低いことから診断が難しく、また病変が進行しないと診断基準に適合しない症例も存在し、診断に苦慮することもしばしばある。本疾患群では、耳鼻咽喉科領域をおかす疾患として最も多いのは多発血管炎性肉芽腫症である。本疾患は、プレドニゾロンとシクロフォスファミドの併用療法の確立により患者の生存期間が飛躍的に改善した。","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"雑誌掲載版","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_relation_27":{"attribute_name":"医中誌ID","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"2012196559","subitem_relation_type_select":"ICHUSHI"}}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-2067","subitem_source_identifier_type":"PISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"2012196559"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"729"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"961"}]},"item_5_text_7":{"attribute_name":"著者 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