{"created":"2023-06-19T11:24:00.648208+00:00","id":4649,"links":{},"metadata":{"_buckets":{"deposit":"79a9f3af-8ab5-492b-b2cc-93e612f174ff"},"_deposit":{"created_by":3,"id":"4649","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"4649"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00004649","sets":["7","7:23"]},"author_link":["14385","14386","14387","14388","14389","14390","14391"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-09-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"9","bibliographicPageEnd":"480","bibliographicPageStart":"475","bibliographicVolumeNumber":"58","bibliographic_titles":[{"bibliographic_title":"泌尿器科紀要"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"何らかのα1遮断薬を3ヵ月以上服用し、かつ抗コリン薬を服用していない前立腺体積が30ml以上の患者でIPSSが8点もしくはQOLインデックスが3点以上の患者72名を対象に、α1遮断薬で十分効果が得られていない前立腺肥大症(BPH)患者に対するデュタステリドの追加投与が切迫性尿失禁を含めた過活動膀胱(OAB)の改善に寄与するか検討した。患者は51〜92歳、平均74.9歳で、非OAB患者25名、OAB患者47名、投与されていたα1遮断薬はシロドシン48名、タムスロシン14名、ナフトピジル10名であった。デュタステリド投与前の各スコアはIPSSが17.2、排尿症状スコア9.3、蓄尿症状スコア7.8、QOLインデックス4.4、OABSS6.9であった。デュタステリド投与後12週でIPSS、排尿症状スコア、蓄尿症状スコアおよびQOLインデックスは投与前と比べ有意に改善し、24週後ではそれぞれ、平均で4.2、2.2、1.9、0.8の改善が認められた。OABSSはデュタステリド投与後、24週後で有意な改善が認められた。非OAB患者ではOABSS、OABSSの各スコアの変化を認めず、OAB患者では12週後から投与前に比べOABSSの有意な改善を認め、24週後で平均1.9の改善が認められた。","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"著者最終原稿版","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0018-1994","subitem_source_identifier_type":"PISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"2013039132"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"788"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"293"}]},"item_5_text_7":{"attribute_name":"著者 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