{"created":"2023-06-19T11:23:46.685857+00:00","id":4374,"links":{},"metadata":{"_buckets":{"deposit":"0230d1e2-3825-4e2c-9cbd-2a248f54b002"},"_deposit":{"created_by":3,"id":"4374","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"4374"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00004374","sets":["7","7:23"]},"author_link":["13551","13552","13553"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-06-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"Suppl","bibliographicPageEnd":"14","bibliographicPageStart":"9","bibliographicVolumeNumber":"83","bibliographic_titles":[{"bibliographic_title":"日本内分泌学会雑誌"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"手術施行下垂体腺腫58例を再発・再増大の11例(男7例・女4例・平均56.3歳:A群)と初発の47例(男20例・女27例・平均47.3歳:B群)に分けて比較した。B群で再発・再増大までの期間は平均6年10ヵ月で、10年前後の長期経過例と1年前後の短期例が存在した。両群間で年齢・性別に有意差はなく、ホルモン産生能も有意差がなかった。画像所見では腫瘍の大きさ、海綿静脈洞浸潤の有無とも有意差はなかった。病理組織所見では、HE所見、CD31免疫染色による血管密度、VEGF免疫染色による血管新生に有意差はなかったが、MIB-1標識率はA群2.0%、B群1.05%とB群が低値の傾向で、再増大を繰り返した1例では経過に伴って上昇していた。p-53免疫染色は全例陰性であった。B群に対する治療は、7例に再手術を、2例に放射線照射を追加し、他の1例は薬物治療、残り1例は手術あるいは放射線照射を予定している。最長5年の経過観察で、再度の再発・再増大は認めていない。","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"雑誌掲載版","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0029-0661","subitem_source_identifier_type":"PISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"2007336547"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"519"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"581"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Hayashi, Yoshimitsu"},{"subitem_text_language":"en","subitem_text_value":"Tanaka, Tatsuya"},{"subitem_text_language":"en"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"程塚, 明","creatorNameLang":"ja"},{"creatorName":"ホドヅカ, アキラ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"13551","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"林, 恵充","creatorNameLang":"ja"},{"creatorName":"ハヤシ, ヨシミツ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"13552","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田中, 達也","creatorNameLang":"ja"},{"creatorName":"タナカ, タツヤ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"13553","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"5138.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"5138.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/4374/files/5138.pdf"},"version_id":"74b52e5b-ed2e-4fdb-b87d-fff330d075f8"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"当科における下垂体腺腫再発ないし再増大例の検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"当科における下垂体腺腫再発ないし再増大例の検討","subitem_title_language":"ja"}]},"item_type_id":"5","owner":"3","path":["6","7","23"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2013-04-08"},"publish_date":"2013-04-08","publish_status":"0","recid":"4374","relation_version_is_last":true,"title":["当科における下垂体腺腫再発ないし再増大例の検討"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2024-07-26T08:56:14.351745+00:00"}