{"created":"2023-06-19T11:23:35.850116+00:00","id":4161,"links":{},"metadata":{"_buckets":{"deposit":"4f5402f8-6d53-4969-a7cc-9a4161c07610"},"_deposit":{"created_by":3,"id":"4161","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"4161"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00004161","sets":["7","7:23"]},"author_link":["12714","12715"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-11-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"11","bibliographicPageEnd":"1012","bibliographicPageStart":"1007","bibliographicVolumeNumber":"29","bibliographic_titles":[{"bibliographic_title":"カレントテラピー"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"進行非小細胞肺癌(non-smallcell lung cancer :N SCLC)に対する治療において，分子生物学的特性を理解したうえで治療戦略を構築すること，いわゆる「個別化治療Jの重要性が増してきた. 2010年10月に改訂されたrEBMの手法による肺癌診療ガイドラインJでは，より有効で安全な肺癌に対する化学療法のために組織型あるいはEGFR遺伝子変異の情報を得ることが治療選択の“鍵\"とされている.抗血管内皮増殖因子(VEGF)抗体「ベパシズマブj療法においては，臨床試験の解析から[肩平上皮癌jが肺出血の予測因子として報告された.またベメ卜レキセド療法においては，複数の臨床試験のサブ解析で[非肩平上皮癌jが効果予測因子として示された今後，抗癌剤の作用機序に基づいた効果予測バイオマーカーの探索，薬剤耐性の機序解明など，基礎研究との連携が一層重要となってくる.","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"雑誌掲載版 佐々木高明　大崎能伸","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0287-8445","subitem_source_identifier_type":"PISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"2012043142"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"589"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"1238"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Ohsaki, Yoshinobu"},{"subitem_text_language":"en"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"佐々木, 高明","creatorNameLang":"ja"},{"creatorName":"ササキ, タカアキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"12714","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大崎, 能伸","creatorNameLang":"ja"},{"creatorName":"オオサキ, ヨシノブ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"12715","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"4883.pdf","filesize":[{"value":"956.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"4883.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/4161/files/4883.pdf"},"version_id":"82c3e057-f4eb-4f0b-b32e-c5173984091e"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"【肺癌-パラダイムシフトを迎えた肺癌治療】 肺癌の診断と治療の最前線　進行非小細胞肺癌の治療選択と組織型","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"【肺癌-パラダイムシフトを迎えた肺癌治療】 肺癌の診断と治療の最前線　進行非小細胞肺癌の治療選択と組織型","subitem_title_language":"ja"}]},"item_type_id":"5","owner":"3","path":["6","7","23"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2012-10-24"},"publish_date":"2012-10-24","publish_status":"0","recid":"4161","relation_version_is_last":true,"title":["【肺癌-パラダイムシフトを迎えた肺癌治療】 肺癌の診断と治療の最前線　進行非小細胞肺癌の治療選択と組織型"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2024-07-26T09:03:38.508404+00:00"}