{"created":"2023-06-19T11:23:28.699515+00:00","id":4023,"links":{},"metadata":{"_buckets":{"deposit":"435a6ab8-84e8-45ed-8457-7d293fc7b4a5"},"_deposit":{"created_by":3,"id":"4023","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"4023"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00004023","sets":["7","7:23"]},"author_link":["12202","12203","12204","12205","12206"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-11-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"245","bibliographicPageStart":"241","bibliographicVolumeNumber":"24","bibliographic_titles":[{"bibliographic_title":"日本小児腎臓病学会雑誌"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"症例は19歳女性。新生児期、腸回転異常症に対し空腸回腸吻合術が施行され、残存小腸6cmの短腸症候群を生じたため、乳児期より在宅中心静脈栄養管理が行われていた。19歳時に全身倦怠感と浮腫、蛋白尿・血尿、低補体血症が出現し、腎生検により膜性増殖性糸球体腎炎と診断された。本腎炎に対するステロイド隔日治療開始にあたり、短腸症候群による吸収障害を考慮し、一定期間プレドニゾロン(PSL)経静脈投与を施行後、内服投与に変更した。吸収効率を評価するために測定した尿中遊離コルチゾール値は、投与日にPSLとの交差を反映し高値を、非投与日に副腎皮質機能抑制により低値を示し、その変動パターンには投与法による差異が認められなかった。以上から短腸症候群を有する本症例においては、経口PSL治療が可能であると判断した。また、内因性ステロイドホルモン分泌の指標となる尿中遊離コルチゾール測定は、ステロイド治療中の副腎機能評価に有用であると考えられた。","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"雑誌掲載版","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0915-2245","subitem_source_identifier_type":"PISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"2012087498"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"1125"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"1321"}]},"item_5_text_7":{"attribute_name":"著者 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