{"created":"2023-06-19T11:23:22.090138+00:00","id":3890,"links":{},"metadata":{"_buckets":{"deposit":"bd224fe9-0e82-441d-a6cb-a6079011aef4"},"_deposit":{"created_by":3,"id":"3890","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3890"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00003890","sets":["7","7:23"]},"author_link":["11698","11699","11700","11701","11702","11703"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-09-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"173","bibliographicPageStart":"172","bibliographicVolumeNumber":"25","bibliographic_titles":[{"bibliographic_title":"耳鼻咽喉科免疫アレルギー"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"鼻性NK/T細胞リンパ腫細胞株と他のリンパ腫・白血病細胞株、健常人より分離した末梢血リンパ球(PBMC)間で遺伝子発現の差を比較検討し、鼻性NK/T細胞リンパ腫細胞株で高発現している遺伝子を検索した。鼻性NK/T細胞リンパ腫細胞株はNK細胞型としてSNK-6、SNK-1、γδT細胞型としてSNT-8を用いた。またその他NK細胞株としてKAI3、YT、NK-92、T細胞株としてJurkat、MOLT-4、PEER、CD70およびCD27の陽性コントロールとしてバーキットリンパ腫細胞株のRajiを用いた。cDNAアレイにてSNK-6とSNT-8、NK-92、健常人PBMCの遺伝子発現差をみると、SNK-6とSNT-8にてCD70の遺伝子発現上昇を認めた。CD70は鼻性NK/T細胞リンパ腫細胞株を含むEBウイルス陽性LMP-1陽性細胞株において発現が認められた。CD70のレセプターであるCD27の発現は鼻性NK/T細胞リンパ腫細胞株では認められなかった。","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"雑誌掲載版 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Shigetaka"},{"subitem_text_language":"en","subitem_text_value":"Takahara, Miki"},{"subitem_text_language":"en","subitem_text_value":"Ogino, Takeshi"},{"subitem_text_language":"en","subitem_text_value":"Harabuchi, Yasuaki"},{"subitem_text_language":"en"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"長門, 利純","creatorNameLang":"ja"},{"creatorName":"ナガト, トシヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"11698","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岸部, 幹","creatorNameLang":"ja"},{"creatorName":"キシベ, カン","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"11699","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森合, 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