{"created":"2023-06-19T11:23:21.734572+00:00","id":3882,"links":{},"metadata":{"_buckets":{"deposit":"b7f57788-aded-49f5-aa0d-82e8329451d2"},"_deposit":{"created_by":3,"id":"3882","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3882"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00003882","sets":["7","7:23"]},"author_link":["11683"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-06-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"12","bibliographicPageStart":"7","bibliographicVolumeNumber":"56","bibliographic_titles":[{"bibliographic_title":"北海道外科雑誌"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"増加する乳癌に対する治療は、乳癌は乳管壁(基底膜)を浸潤した段階で微小転移(micrometastasis)の可能性があり、局所治療(手術、放射線治療)だけではなく、積極的な全身治療(薬物療法)が重要という考え方を基本方針としている。初期治療(術前、術後補助療法)は治癒を目指す治療であり、転移再発時の治療は生存期間の延長、症状緩和、QOLの維持向上に重きを置いた治療となる。薬物決定は、形態学(解剖学)的特性である、腫瘍の大きさやリンパ節転移の有無だけではなく、生物学的特性である、腫瘍の悪性度(Grade、Ki-67)や生物学的特性(Hormon receptor、HER2)を良く見極め、効果、overall survival(OS)の改善などを検討し、決定すべきである。また、更なる個別化治療を目指し、遺伝子発現プロファイルによるSubtype分類に基づいた薬物療法の選択は今後発展していくと思われる。","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"雑誌掲載版","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0288-7509","subitem_source_identifier_type":"PISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"2011325942"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"819"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"386"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"北田, 正博","creatorNameLang":"ja"},{"creatorName":"キタダ, マサヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"11683","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"4597.pdf","filesize":[{"value":"6.8 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"4597.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/3882/files/4597.pdf"},"version_id":"0b9f0707-a5be-4240-959e-c20bb8b92e75"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"乳癌薬物治療","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"外科と化学療法　乳癌の薬物療法","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"外科と化学療法　乳癌の薬物療法","subitem_title_language":"ja"}]},"item_type_id":"5","owner":"3","path":["6","7","23"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2012-06-13"},"publish_date":"2012-06-13","publish_status":"0","recid":"3882","relation_version_is_last":true,"title":["外科と化学療法　乳癌の薬物療法"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2024-07-26T08:59:00.296020+00:00"}