{"created":"2023-06-19T11:23:04.960830+00:00","id":3556,"links":{},"metadata":{"_buckets":{"deposit":"7f5afcf0-cbe1-44de-b056-27e72fffa64b"},"_deposit":{"created_by":3,"id":"3556","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3556"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00003556","sets":["7","7:23"]},"author_link":["10200","10201","10202","10203","10204","10205","10206","10207","10208","10209"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1994-10-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"10","bibliographicPageEnd":"2724","bibliographicPageStart":"2721","bibliographicVolumeNumber":"14","bibliographic_titles":[{"bibliographic_title":"Progress in Medicine"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ラットにprednisolone 4mg/kg/日 4日間投与,または水浸拘束によるストレス潰瘍を作り,それに対するDHEA-Sの効果を検討した。prednisoloneによる胃粘膜病変は,同時に皮下注射したDHEA-S (50-200mg/kg)によって用量依存性に抑制され,prednisoloneによる胸腺萎縮も予防された。水浸拘束ストレス潰瘍の発生もDHEA-S前投与によって抑制された。ストレス潰瘍の外来患者30例について尿中17-KS-S (DHEA-S代謝産物),17-OHCS (Cortisol代謝産物)を測定した所,17-OHCSは上昇,17KS-Sおよび17KS-S/17-OHCS比は低値であった。ストレス状態ではcortisolとDHEA-S分泌バランスの変化が消化性潰瘍発生,胸腺萎縮に関与していると思われる","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"雑誌掲載版","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0287-3648","subitem_source_identifier_type":"PISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"1995130657"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"1040"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"759"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Shaku, Fumio"},{"subitem_text_language":"en","subitem_text_value":"Kubo, Kouji"},{"subitem_text_language":"en","subitem_text_value":"Kubota, Tatsuya"},{"subitem_text_language":"en","subitem_text_value":"Nozu, Tsukasa"},{"subitem_text_language":"en","subitem_text_value":"Moriya, Mitsuru"},{"subitem_text_language":"en","subitem_text_value":"Watanabe, Yasuo"},{"subitem_text_language":"en","subitem_text_value":"Shoji, Etsuro"},{"subitem_text_language":"en"},{"subitem_text_value":"Harada, Kazumichi"},{"subitem_text_language":"en"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"上原, 聡","creatorNameLang":"ja"},{"creatorName":"ウエハラ, アキラ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"10200","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"釈, 文雄","creatorNameLang":"ja"},{"creatorName":"シャク, フミオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"10201","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"久保, 光司","creatorNameLang":"ja"},{"creatorName":"クボ, コウジ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"10202","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"久保田, 達也","creatorNameLang":"ja"},{"creatorName":"クボタ, タツヤ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"10203","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"野津, 司","creatorNameLang":"ja"},{"creatorName":"ノヅ, ツカサ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"10204","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森谷, 満","creatorNameLang":"ja"},{"creatorName":"モリヤ, ミツル","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"10205","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"渡邊, 泰男","creatorNameLang":"ja"},{"creatorName":"ワタナベ, ヤスオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"10206","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小路, 悦郎","creatorNameLang":"ja"},{"creatorName":"ショウジ, エツロウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"10207","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Severino, B. 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