{"created":"2023-06-19T11:22:59.298967+00:00","id":3445,"links":{},"metadata":{"_buckets":{"deposit":"fd3b79f2-dee2-45dd-bc0f-0dc090b55c19"},"_deposit":{"created_by":3,"id":"3445","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3445"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00003445","sets":["7","7:23"]},"author_link":["9492","9493","9494","9495"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-04-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"861","bibliographicPageStart":"853","bibliographicVolumeNumber":"61","bibliographic_titles":[{"bibliographic_title":"最新医学"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"高血圧は圧負荷により左室肥大・左室リモデリングから心不全を,また他の危険因子との相乗効果により冠動脈硬化を発症させ,心血管イベントのリスクを高める.長時間作用型Ca拮抗薬は降圧効果が的確で,冠拡張作用,抗酸化作用,抗動脈硬化作用を有する.一方,アンジオテンシンII受容体拮抗薬(ARB)はアンジオテンシン変換酵素(ACE)阻害薬とともに心肥大退縮,心室リモデリング抑制,新規糖尿病・心房細動発症抑制効果に優れている.最近のエビデンスから,心疾患合併高血圧に対してはまず病態に応じた降圧薬の併用による確実な降圧を優先し,次いでさらなる心血管保護を考慮することが勧められる","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"雑誌掲載版","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0370-8241","subitem_source_identifier_type":"ISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"2006148379"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"976"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"856"}]},"item_5_text_7":{"attribute_name":"著者 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