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A patient with familial Mediterranean fever mimicking diarrhea-dominant irritable bowel syndrome who successfully responded to treatment with colchicine: a case report

https://asahikawa-med.repo.nii.ac.jp/records/2000509
https://asahikawa-med.repo.nii.ac.jp/records/2000509
b7dd7ab6-b1a0-4635-8178-999c5da46ff3
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35739566.pdf 35739566.pdf (1.2 MB)
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Item type 学術雑誌論文 / Journal Article_02(1)
公開日 2025-05-26
タイトル
タイトル A patient with familial Mediterranean fever mimicking diarrhea-dominant irritable bowel syndrome who successfully responded to treatment with colchicine: a case report
言語 en
言語
言語 eng
キーワード
主題Scheme Other
キーワード Colchicine
キーワード
主題Scheme Other
キーワード Familial Mediterranean fever
キーワード
主題Scheme Other
キーワード Irritable bowel syndrome
資源タイプ
資源タイプ journal article
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
著者 Shima, Kumei

× Shima, Kumei

en Shima, Kumei

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Masatomo, Ishioh

× Masatomo, Ishioh

en Masatomo, Ishioh

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Yuki, Murakami

× Yuki, Murakami

en Yuki, Murakami

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Katsuyoshi, Ando

× Katsuyoshi, Ando

en Katsuyoshi, Ando

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Tsukasa, Nozu

× Tsukasa, Nozu

en Tsukasa, Nozu

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Toshikatsu, Okumura

× Toshikatsu, Okumura

en Toshikatsu, Okumura

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bibliographic_information en : Journal of medical case reports

巻 16, 号 1, p. 247, 発行日 2022-06-24
ISSN
収録物識別子タイプ EISSN
収録物識別子 1752-1947
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.1186/s13256-022-03446-z
リンクURL
内容記述タイプ Other
内容記述 https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-022-03446-z
言語 en
item_1716186501932
関連タイプ isIdenticalTo
識別子タイプ PMID
関連識別子 35739566
item_5_description_33
内容記述タイプ Abstract
内容記述 Background: Irritable bowel syndrome is a functional gastrointestinal disease. Visceral hypersensitivity is the most important pathophysiology in irritable bowel syndrome. Currently, diagnosis of irritable bowel syndrome is based on symptoms and exclusion of other organic diseases. Although the diagnosis of irritable bowel syndrome can be made based on the Rome IV criteria, one may speculate that complete exclusion of other organic diseases is not so easy, especially in cases uncontrolled with standard therapies.

Case presentation: We present herein a case of familial Mediterranean fever in a young Japanese patient who had been suffering from an irritable bowel syndrome-like clinical course. A 25-year-old Japanese male had been diagnosed as having diarrhea-predominant irritable bowel syndrome 5 years earlier. Unfortunately, standard therapies failed to improve irritable bowel syndrome symptoms. After careful medical history-taking, we understood that he had also experienced periodic fever since 10 years ago. Although no mutation was identified in the Mediterranean fever gene, not only periodic fever but abdominal symptoms improved completely after colchicine administration. He was therefore diagnosed as having familial Mediterranean fever and that the abdominal symptoms may be related to the disease.

Conclusions: Familial Mediterranean fever should be considered as a cause of irritable bowel syndrome-like symptoms.
言語 en
注記
内容記述タイプ Other
注記 This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.
言語 en
出版タイプ
出版タイプ VoR
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en
© 2022. The Author(s).
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