{"created":"2023-06-19T11:21:35.095895+00:00","id":1826,"links":{},"metadata":{"_buckets":{"deposit":"49666f20-75a6-4fec-9981-fa31a2d93603"},"_deposit":{"created_by":3,"id":"1826","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"1826"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00001826","sets":["7","7:19:25"]},"author_link":["5565","5566","5567","5568","5569","5570","5571","5572"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2002-03-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"28","bibliographicPageStart":"23","bibliographicVolumeNumber":"22","bibliographic_titles":[{"bibliographic_title":"てんかんをめぐって"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"28歳男.26歳時けいれい発作が出現し,遺伝子検査の結果,ミトコンドリアDNAの3243番目に点変異を認め,mitchondrial myopathy,encephalopaty,lactic acidosis,and strokelike episodes(MELAS)と診断された.phenytoin及びubidecarenoneの薬物療法が開始された.その後,口部自動症から両上肢を痙攣させる発作が出現し,頭部CTで両側基質核の石灰化がみられた.zomisamide及びphenobarbitalが投与されたが,次第に退行した様子となり,短絡的言動を示すようになった.知能低下と躁状態を認め,演技的な痙攣発作を繰り返したが,脳波では発作波は認められず,PPSと考えられた.抗癲癇薬の変更によりPPS及び躁状態が出現したことから,phenobarbitalとzonisamideを中止した.中止後の脳血流SPECT等の検査結果より,真の痙攣発作を起こす可能性が高いと考えられ,carbamazepineを開始した.PPSや躁状態は1ヵ月ほどで消失し,退院となり,現在まで再発はみられていない","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"出版社版","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1349-3078","subitem_source_identifier_type":"ISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"2003309822"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"1873"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"1892"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Ishimoto, Takahiro"},{"subitem_text_language":"en","subitem_text_value":"Chiba, Shigeru"},{"subitem_text_language":"en","subitem_text_value":"Takasaki ,Hideki"},{"subitem_text_language":"en","subitem_text_value":"Tabata, Kazuki"},{"subitem_text_language":"en","subitem_text_value":"Ishimaru, Yuji"},{"subitem_text_language":"en","subitem_text_value":"Omori, Nobuyuki"},{"subitem_text_language":"en","subitem_text_value":"Tamura, Yoshiyuki"},{"subitem_text_language":"en","subitem_text_value":"Mera, Kazuhiko"},{"subitem_text_language":"en"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"石本, 隆広","creatorNameLang":"ja"},{"creatorName":"イシモト, タカヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"5565","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"千葉, 茂","creatorNameLang":"ja"},{"creatorName":"チバ, 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