{"created":"2023-06-19T11:21:11.599268+00:00","id":1344,"links":{},"metadata":{"_buckets":{"deposit":"ee64fdb3-9448-415f-ae1b-674f4ce61e74"},"_deposit":{"created_by":3,"id":"1344","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"1344"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00001344","sets":["6:29:30","7","7:24"]},"author_link":["4345","4346","4347","4348","4349","4350","4351","4352","4353","4354","4355","4356","4357","4358"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"252","bibliographicPageStart":"243","bibliographicVolumeNumber":"56","bibliographic_titles":[{"bibliographic_title":"Journal of Histochemistry and Cytochemistry"}]}]},"item_5_description_25":{"attribute_name":"リンクURL","attribute_value_mlt":[{"subitem_description":"http://dx.doi.org/10.1369/jhc.7A7312.2007 | http://dx.doi.org/10.1369/jhc.7A7312.2007","subitem_description_type":"Other"}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We have recently identified a novel collectin, CL-K1, that may play a role in innate immunity as a member of the collectin family. In this study using mice, we investigated the tissue distribution of CL-K1 for better understanding of its pathophysiological relevance. Real-time PCR analyses demonstrated that CL-K1 mRNA was expressed in all tissues tested. Immunohistochemical analyses demonstrated that CL-K1 was expressed in proximal tubules of kidney, in mucosa of the gastrointestinal tract, and in bronchial glands of bronchioles similar to the localization of SP-A and SP-D in these pulmonary structures. Immunohistochemistry also showed that CL-K1 was highly expressed in hepatocytes around the central veins in liver, which suggests that murine CL-K1 might be mainly produced in theliver and secreted into the blood stream as is human CL-K1. CL-K1 was especially detected in vascular smooth muscle in several types of tissue. In addition, it was also expressed in intestinal Paneth cells, in mesangial cells of kidney, in pancreatic islet D cells, and in neurons of the brain. It is of interest that this profile of CL-K1 expression is unique among the collectins. Taken together, these histological findings may be useful for the understanding biological function of this novel collectin.","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"author","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_relation_24":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1369/jhc.7A7312.2007","subitem_relation_type_select":"DOI"}}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0022-1554","subitem_source_identifier_type":"ISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"18040075"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"3138"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"1398"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Wakamiya, Nobutaka"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"若宮, 伸隆"},{"creatorName":"ワカミヤ, ノブタカ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4345","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Motomura, W"}],"nameIdentifiers":[{"nameIdentifier":"4346","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshizaki, T"}],"nameIdentifiers":[{"nameIdentifier":"4347","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ohtani, K"}],"nameIdentifiers":[{"nameIdentifier":"4348","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okumura, T"}],"nameIdentifiers":[{"nameIdentifier":"4349","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fukuda, M"}],"nameIdentifiers":[{"nameIdentifier":"4350","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fukuzawa, J"}],"nameIdentifiers":[{"nameIdentifier":"4351","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mori, K"}],"nameIdentifiers":[{"nameIdentifier":"4352","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Jang, SJ"}],"nameIdentifiers":[{"nameIdentifier":"4353","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nomura, N"}],"nameIdentifiers":[{"nameIdentifier":"4354","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshida, I"}],"nameIdentifiers":[{"nameIdentifier":"4355","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Y"}],"nameIdentifiers":[{"nameIdentifier":"4356","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kohgo, Y"}],"nameIdentifiers":[{"nameIdentifier":"4357","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Wakamiya, N"}],"nameIdentifiers":[{"nameIdentifier":"4358","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"1608.pdf","filesize":[{"value":"2.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"1608.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/1344/files/1608.pdf"},"version_id":"34788f49-2372-4396-826f-18d6cd3e2a51"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Immunolocalization of a Novel Collectin CL-K1 in Murine Tissues","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Immunolocalization of a Novel Collectin CL-K1 in Murine Tissues","subitem_title_language":"en"}]},"item_type_id":"5","owner":"3","path":["7","24","30"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2009-03-11"},"publish_date":"2009-03-11","publish_status":"0","recid":"1344","relation_version_is_last":true,"title":["Immunolocalization of a Novel Collectin CL-K1 in Murine Tissues"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2024-04-19T11:24:37.972837+00:00"}