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【シックハウスの実態と対応方策について】 シックハウス症候群への湿度環境・生物学的汚染の影響 西條, 泰明 サイジョウ, ヤスアキ 吉田, 貴彦 ヨシダ, タカヒコ 岸, 玲子 キシ, レイコ sick building syndrome dampness mold condensation higher humidity moldy odor mite allergen Sick house syndrome is caused by not only chemicals but also dampness and biological factors. Many European and North American studies have shown that dampness associated with condensation, visible mold, moldy odor, and water-induced damage among others affects residents’ health. Recent Japanese studies have also shown a similar significant relationship. Mold can cause infection and allergy, and can produce chemicals such as microbial volatile organic compounds (MVOCs) and 1→3?β?D?glucan. Mold exposure can be analyzed using culture-based (colony forming unit count) enumeration techniques. More recently, other nonculture-based methods of measuring mold concentrations in indoor environments have been described, which may provide more valid measures of exposure. These are based on measurement of specific mold markers in dust or air, such as ergosterol, genus-specific extracellular polysaccharides or 1→3?β?D?glucan. Mites are major indoor allergens. The gold standard for measuring exposure to mite allergens is enzyme-linked immunosorbent assay (ELISA), but it is relatively expensive and requires specialized techniques. Several simple semiquantitative dust mites allergen test have b available in Japan. 著者最終原稿版 text application/pdf 2009-05-01 jpn journal article AM https://asahikawa-med.repo.nii.ac.jp/records/2079 0021-5082 日本衛生学雑誌 64 3 665 671 https://asahikawa-med.repo.nii.ac.jp/record/2079/files/2844.pdf application/pdf 427.2 kB 2021-07-06